Jason Gotlib Selected Research

BCR-ABL Negative Atypical Chronic Myeloid Leukemia (Leukemia, Myeloid, Philadelphia Negative)

1/2020	Efficacy of Ruxolitinib in Patients With Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia.
2/2016	The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
9/2013	The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment.

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Jason Gotlib Research Topics

Disease

43	Neoplasms (Cancer) 01/2022 - 02/2004
27	Systemic Mastocytosis 11/2022 - 10/2005
22	Primary Myelofibrosis (Myelosclerosis) 01/2022 - 01/2012
20	Eosinophilia 01/2022 - 01/2005
13	Mastocytosis 01/2022 - 08/2006
13	Pdgfra-Associated Chronic Eosinophilic Leukemia 01/2022 - 04/2004
13	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 01/2005
12	Hypereosinophilic Syndrome (Loeffler Endocarditis) 12/2015 - 03/2003
10	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 11/2020 - 10/2003
8	Anemia 11/2019 - 11/2006
7	Leukemia 01/2022 - 03/2004
7	Splenomegaly 01/2018 - 10/2013
6	Hypersensitivity (Allergy) 01/2022 - 01/2021
6	Polycythemia Vera 01/2022 - 04/2006
6	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 01/2008
5	Essential Thrombocythemia 01/2022 - 01/2012
5	Mast Cell Activation Disorders (Mast-Cell Disease) 01/2022 - 08/2006
5	Blast Crisis (Blast Phase) 12/2020 - 08/2004
5	Thrombocytopenia (Thrombopenia) 11/2019 - 03/2012
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/2014 - 04/2004
4	Thrombocytosis (Thrombocythemia) 01/2022 - 12/2011
4	Myeloproliferative Disorders (Myeloproliferative Disorder) 07/2006 - 01/2005
3	Thrombosis (Thrombus) 12/2022 - 03/2014
3	Chronic Neutrophilic Leukemia 01/2020 - 09/2013
3	BCR-ABL Negative Atypical Chronic Myeloid Leukemia (Leukemia, Myeloid, Philadelphia Negative) 01/2020 - 09/2013
2	Hereditary alpha-tryptasemia syndrome 01/2022 - 11/2021
2	Chromosome Aberrations (Chromosome Abnormalities) 01/2021 - 03/2003
2	Philadelphia Chromosome 01/2021 - 01/2018
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021 - 12/2014
2	Multiple Myeloma 09/2018 - 04/2016
2	Lymphoma (Lymphomas) 10/2017 - 01/2017
2	Fever (Fevers) 03/2017 - 04/2014
2	Fatigue 01/2017 - 04/2013
2	Mast-Cell Leukemia (Leukemia, Mast Cell) 06/2016 - 10/2005
2	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 02/2010 - 01/2005
1	von Willebrand Diseases (von Willebrand's Disease) 01/2022
1	Anaphylaxis (Anaphylactic Shock) 01/2021
1	Osteoporosis 01/2021

Drug/Important Bio-Agent (IBA)

19	ruxolitinibIBA 10/2021 - 03/2012
16	Imatinib Mesylate (Gleevec)FDA Link 12/2020 - 03/2003
14	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 01/2022 - 01/2006
12	Phosphotransferases (Kinase)IBA 01/2017 - 02/2004
9	Tryptases (Tryptase)IBA 01/2022 - 10/2014
9	midostaurinIBA 01/2022 - 10/2005
8	Janus Kinase InhibitorsIBA 01/2022 - 01/2013
8	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020 - 03/2003
8	Tyrosine Kinase InhibitorsIBA 01/2018 - 05/2003
8	Tyrosine (L-Tyrosine)FDA Link 01/2017 - 02/2004
6	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2019 - 08/2006
5	avapritinibIBA 11/2022 - 12/2021
5	Biological ProductsIBA 01/2022 - 01/2012
5	Proteins (Proteins, Gene)FDA Link 11/2020 - 03/2004
5	Janus KinasesIBA 01/2018 - 08/2010
5	Janus Kinase 1IBA 01/2018 - 12/2013
4	CalreticulinIBA 01/2022 - 03/2014
4	Biomarkers (Surrogate Marker)IBA 10/2021 - 04/2014
4	Janus Kinase 2IBA 01/2021 - 12/2013
4	CytokinesIBA 01/2021 - 01/2006
3	Pharmaceutical PreparationsIBA 01/2022 - 03/2012
3	Cladribine FDA LinkGeneric 01/2022 - 08/2006
3	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2022 - 10/2020
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021 - 10/2005
3	Core Binding Factors (Core-Binding Factor)IBA 01/2021 - 01/2018
3	Thrombopoietin (c-mpl Ligand)IBA 06/2014 - 12/2011
3	Farnesyltranstransferase (Farnesyltransferase)IBA 03/2008 - 01/2005
2	Immunoglobulin E (IgE)IBA 01/2022 - 01/2022
2	Alkaline PhosphataseIBA 01/2021 - 12/2019
2	Azacitidine (5 Azacytidine)FDA Link 11/2020 - 01/2016
2	Hemoglobins (Hemoglobin)IBA 11/2019 - 03/2014
2	Lenalidomide (CC 5013)FDA Link 09/2018 - 01/2016
2	AntibodiesIBA 01/2018 - 12/2015
2	Interferon-alpha (Interferon Alfa)IBA 10/2016 - 08/2006
2	Mitoxantrone (Novantrone)FDA LinkGeneric 12/2014 - 11/2010
2	Etoposide (VP 16)FDA LinkGeneric 12/2014 - 11/2010
2	Cytarabine (Cytosar-U)FDA LinkGeneric 12/2014 - 11/2010
2	Erythropoietin FDA Link 06/2014 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 11/2013 - 12/2012
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 09/2013 - 01/2009
2	Interleukin-5 (Interleukin 5)IBA 04/2012 - 01/2006
2	Dasatinib (BMS 354825)FDA Link 08/2011 - 08/2006
2	mepolizumabIBA 03/2010 - 02/2010
2	Alemtuzumab (Campath)FDA Link 03/2010 - 02/2010
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 02/2010 - 01/2005
2	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 02/2010 - 01/2006
2	beta CateninIBA 03/2009 - 08/2004
2	tipifarnib (R115777)IBA 03/2008 - 02/2007
2	Platelet-Derived Growth Factor alpha ReceptorIBA 01/2005 - 03/2003
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2022
1	Arthropod VenomsIBA 01/2022
1	Genetic Markers (Genetic Marker)IBA 01/2022
1	anagrelide (Agrylin)FDA LinkGeneric 01/2022
1	RNA (Ribonucleic Acid)IBA 12/2021
1	Syntex adjuvant formulationIBA 01/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2021
1	GTP Phosphohydrolases (GTPases)IBA 01/2021

Therapy/Procedure

42	Therapeutics 12/2022 - 10/2003
5	Drug Therapy (Chemotherapy) 01/2020 - 11/2010
2	Cell Transplantation 01/2018 - 01/2016
2	Hematopoietic Stem Cell Transplantation 01/2017 - 10/2016